There are two main ways for Nipah to spread to humans. The first is through the consumption of fruits or fruit products contaminated with the bodily fluids (urine, saliva) of a Flying Fox bat infected with Nipah. This method of transmission is the main cause of the yearly outbreaks seen in certain parts of Asia. To protect populations from this, methods can be taken on the agricultural end, to prevent the bats from having easy access to the products. One major example of this is in the case of date palm sap, which is a widely consumed product in many countries. It is produced in a habitat to Flying Fox bats, giving them access to the food and leading to contamination. The act of simply covering the dates would prevent the spread of Nipah, while allowing humans and bats to coexist, although adding regulations about the cleaning of fruit would also help protect humans from infection.

The second notable way in which NiV is transmitted from animals to humans is in farms with. Nipah spreads very effectively in domesticated animals, mostly pigs. If farms made sure to hold a limited number of animals within a certain space, it could stop Nipah from spreading as quickly if one animal did get infected. Sanitation policies and requirements in farms could also help prevent NiV from entering farms in the first place and should be taken very seriously.